Application and Function of Malic Acid
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Application and Function of Malic Acid

Views: 0     Author: Site Editor     Publish Time: 2022-10-28      Origin: Site

Malic acid, also known as 2-hydroxysuccinic acid, has two stereoisomers due to an asymmetric carbon atom in the molecule. In nature, it exists in three forms, namely D-malic acid, L-malic acid and its mixture DL malic acid. It is a white crystal or crystalline powder with strong hygroscopicity, easily soluble in water and ethanol, and it has a special pleasant sour taste. Malic acid is mainly used in food and pharmaceutical industries.

Malic acid production method

The production method of L-malic acid has developed from the early single extraction method to the following methods: extraction, chemical synthesis, one-step fermentation, two-step fermentation, immobilized enzyme or cell transformation. At present, the existing problem is still the lack of excellent production strains. While researching and breeding excellent strains, it is necessary to pay attention to strengthening the research on extraction technology and other related technologies, and do a good job in the research and development of supporting technologies for upstream and downstream projects.

Malic acid preparation

(1) Extraction method: Boil the juice of immature apples, grapes, peaches, etc., add lime water to generate calcium salt precipitation, and then generate free malic acid after treatment.Malic acid buy-herb-key

(2) Synthesis method: benzene is catalytic oxidized to obtain maleic acid and fumaric acid, and then hydrated under high temperature and pressure. The conditions for hydration reaction are usually 3-5 h at 180-220'C and 1.4-1.8 MPa. The reaction products are mainly malic acid and a small amount of fumaric acid. Adjust the content of malic acid at 40 ℃ to 40% and cool the solution to about 15'C, filter and separate fumaric acid crystals, concentrate mother liquor, centrifuge and separate solids to obtain crude malic acid, and then refine and crystallize to obtain finished products.

(3) Fermentation method: L-malic acid is produced from fumaric acid by biological enzyme fermentation.

Malic acid application and function

1. Food industry application

L-malic acid is an important component of natural fruit juice. Compared with citric acid, L-malic acid has a high acidity (20% stronger than citric acid), but it tastes soft (with a higher buffer index), has a special flavor, does not damage the mouth and teeth, is metabolically conducive to the absorption of amino acids, and does not accumulate fat. It is a new generation of food acid, and is praised as the "most ideal food acid" by the biological and nutritional circles, Since 2013, citric acid has been replaced in foods for the elderly and children.

L-malic acid is an essential organic acid for human body and an ideal food additive with low calorie. When 50% L-malic acid and 20% citric acid are used together, they can present strong natural fruit flavor.

Beverages (all kinds of cool drinks): soft drinks prepared with L-malic acid are thirst quenching and refreshing, with apple acid taste, close to natural fruit juice. Some large domestic food companies, such as Wahaha Group and Jianlibao Group, began to use L-malic acid in beverages.

L-malic acid is a circulating intermediate of biological tricarboxylic acid. Its taste is close to natural fruit juice and has a natural flavor. Compared with citric acid, L-malic acid produces less heat and tastes better. Therefore, L-malic acid is widely used in wine, beverages, jam, chewing gum and other foods, and has the tendency to gradually replace citric acid. It is one of the organic acids with the largest consumption and good development prospects in the world food industry.

L-malic acid contains natural moisturizing ingredients, which can easily dissolve the "glue" stuck between the dry scaly dead cells, so as to remove the wrinkles on the skin surface and make the skin tender, white, smooth and elastic, so it is favored in cosmetics formulas; L-malic acid can be used to prepare a variety of essence and spices for a variety of daily chemical products, such as toothpaste, shampoo, etc; Compared with citric acid, L-malic acid has a soft and unique sour taste. Therefore, it is used abroad to replace citric acid as a new type of detergent additive to synthesize high-grade special detergents.

L-malic acid can be used to treat liver disease, anemia, low immunity, uremia, hypertension, liver failure and other diseases, and can reduce the toxic effect of anti-cancer drugs on normal cells; It can also be used to prepare and synthesize insect repellents, anti tartar agents, etc.

2. Pharmaceutical industry application

When malic acid is added to various tablets and syrups, the fruit flavor can be presented, and it is conducive to absorption and diffusion in the body. It is often added to the compound amino acid injection to improve the utilization rate of amino acids. Its sodium salt is an effective drug for treating liver dysfunction, especially hypertension. Potassium L-malate is a good potassium supplement, which can maintain the water balance of the human body and treat edema, hypertension and fat accumulation.

L-malic acid can be used in pharmaceutical preparations, tablets, syrups, and can also be added into amino acid solutions, which can significantly improve the absorption rate of amino acids; L-apple can be used to treat liver disease, anemia, low immunity, uremia, hypertension, liver failure and other diseases, reduce the toxic effect of anti-cancer drugs on normal cells, and also be used to prepare and synthesize insect repellents, anti tartar agents, etc. In addition, L-malic acid can also be used as industrial cleaner, resin curing agent, synthetic material plasticizer, feed additive, etc.

3.Daily chemical industry application

Zinc L-malate is used in toothpaste as an antibacterial stain agent, an anti dental calculus agent, and a synthetic flavor formula.

4.Application in chemical industry

It can be used as one of the synthetic materials of scale remover and fluorescent whitening agent. When added to shellac varnish or other varnishes, it can prevent the paint from skinning. The polyester resin and alkyd resin produced with this acid are plastics with special purposes.