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Conjugated linoleic acid (CLA) is a collective term for all mixtures of stereoisomers and positional isomers of linoleic acid, which can be considered as a secondary derivative of linoleic acid with the molecular formula C17H31COOH. The double bonds of conjugated linoleic acid can be located at positions 7 and 9, 8 and 10, 9 and 11, 10 and 12, 11 and 13, 12 and 14, and each double bond has two conformations, cis (cis or c) and trans (trans or t). Theoretically, there are more than 20 isomers of conjugated linoleic acid, and c-9, t-11, and t-10, c-12 are the two isomers with the highest content. Conjugated linoleic acid is absorbed into the bloodstream through the digestive tract and distributed throughout the body in foods. After being absorbed, CLA mainly enters into tissue structural lipids, as well as plasma phospholipids, phospholipids in cell membranes, or arachidonic acid is metabolized in the liver to further synthesize eicosane active substances.
Conjugated linoleic acid is mainly found in the meat and milk of ruminants such as cattle and sheep. This is because the anaerobic linoleic acid isomerase of Vibrio fibrinolyticus in the gut of ruminants can convert linoleic acid into conjugated linoleic acid, mainly in the form of c-9, t-11 isomers. Therefore, natural conjugated linoleic acid mainly exists as microbial metabolites in the digestive tract of ruminants. Conjugated linoleic acid is also present in small amounts in tissues, blood, and body fluids of other animals. Plant foods also contain a small amount of conjugated linoleic acid, but the distribution of its isomers is significantly different from that of animal foods, especially the biologically active c-9, t-11 isomers in plant foods. The content of conjugated linoleic acid in marine food is also low.
1. Conjugated linoleic acid has certain physiological functions such as anti-tumor, anti-oxidation, anti mutation, antibacterial, reducing human cholesterol, anti atherosclerosis, improving immunity, improving bone density, preventing and treating diabetes and promoting growth.
2. Conjugated linoleic acid can increase energy consumption after entering the body, so it can effectively reduce body fat deposition in weight control.
Conjugated linoleic acid (CLA) is a collective term for all mixtures of stereoisomers and positional isomers of linoleic acid, which can be considered as a secondary derivative of linoleic acid with the molecular formula C17H31COOH. The double bonds of conjugated linoleic acid can be located at positions 7 and 9, 8 and 10, 9 and 11, 10 and 12, 11 and 13, 12 and 14, and each double bond has two conformations, cis (cis or c) and trans (trans or t). Theoretically, there are more than 20 isomers of conjugated linoleic acid, and c-9, t-11, and t-10, c-12 are the two isomers with the highest content. Conjugated linoleic acid is absorbed into the bloodstream through the digestive tract and distributed throughout the body in foods. After being absorbed, CLA mainly enters into tissue structural lipids, as well as plasma phospholipids, phospholipids in cell membranes, or arachidonic acid is metabolized in the liver to further synthesize eicosane active substances.
Conjugated linoleic acid is mainly found in the meat and milk of ruminants such as cattle and sheep. This is because the anaerobic linoleic acid isomerase of Vibrio fibrinolyticus in the gut of ruminants can convert linoleic acid into conjugated linoleic acid, mainly in the form of c-9, t-11 isomers. Therefore, natural conjugated linoleic acid mainly exists as microbial metabolites in the digestive tract of ruminants. Conjugated linoleic acid is also present in small amounts in tissues, blood, and body fluids of other animals. Plant foods also contain a small amount of conjugated linoleic acid, but the distribution of its isomers is significantly different from that of animal foods, especially the biologically active c-9, t-11 isomers in plant foods. The content of conjugated linoleic acid in marine food is also low.
1. Conjugated linoleic acid has certain physiological functions such as anti-tumor, anti-oxidation, anti mutation, antibacterial, reducing human cholesterol, anti atherosclerosis, improving immunity, improving bone density, preventing and treating diabetes and promoting growth.
2. Conjugated linoleic acid can increase energy consumption after entering the body, so it can effectively reduce body fat deposition in weight control.
