Cordyceps Extract
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Cordyceps Extract

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Cordyceps extract powder description

Cordyceps sinensis extract is the water extract or alcohol extract of the precious traditional Chinese medicine Cordyceps sinensis. The main active components are nucleoside compounds and polysaccharides, which have anti-inflammatory, anti-tumor, immune enhancement and other effects. It can be used for beautifying and moisturizing, anti wrinkle and whitening, anti-aging, fitness and disease prevention, etc.

Cordyceps mushroom extract extraction source

Cordyceps is Cordyceps sinensis. Cordyceps sinensis is formed by connecting the insect body with the mycelium, with a total length of 9~12cm. The insect body is like an old silkworm, about 3~6cm long and 0.4~0.7cm thick. The appearance is dark yellow and rough. There are many horizontal wrinkles on the back. There are eight pairs on the ventral surface. The four pairs in the middle of the worm are obviously visible. The inner part of the section is substantial, white, slightly yellow, and the periphery is dark yellow. The mycelium is produced from the head of the insect body, which is rod shaped, curved, and slightly expanded at the upper part. The surface is grayish brown or dark brown, up to 4-8 cm long and 0.3 cm in diameter. The heart is empty and pink when it breaks. It smells slightly and tastes light. The insect body is yellow and bright, the section is yellow and white, and the mycelia is short. It is mainly produced in Sichuan, Qinghai, Guizhou and Yunnan. Sichuan has the largest output. In addition, it is also produced in Tibet, Gansu and other places.

pharmacological action

1. Effect on cardiovascular system

Cordyceps sinensis aqueous extract can slow down heart rate, increase cardiac output and coronary flow; The ethanol extract of Cordyceps sinensis injected subcutaneously could increase the intake of 86Rb in myocardium of mice and increase the blood supply to myocardium; The ethanol extracts and fermentation broth of Cordyceps sinensis mycelia also have some protective effects on stress myocardial infarction induced by thyroxine and noradrenaline chemobooks in rats; Continuous oral administration of Cordyceps sinensis powder or Cordyceps sinensis powder or subcutaneous injection of Cordyceps sinensis alcohol extract can significantly reduce serum cholesterol content and plasma β- Lipoprotein; The ethanol extract of Cordyceps sinensis injected intravenously can significantly prolong the latency of arrhythmia induced by aconitine in rats, shorten the duration of arrhythmia, and reduce the degree of arrhythmia.

2. Immune enhancement

The ethanol extract of Cordyceps sinensis or decoction of Cordyceps sinensis can significantly enhance the phagocytic function of monocyte macrophage system by subcutaneous or intraperitoneal injection or intramuscular injection. The volume and nucleus of macrophages increase, the cytoplasm is rich, the particles, vacuoles, phagosomes and lysosomes in cytoplasm increase, and the content of lysozyme in serum increases. It can also antagonize the inhibition of cortisone on macrophage phagocytosis. Cordyceps sinensis can promote lymphocyte transformation by perfusion to rabbits. Intraperitoneal injection of Cordyceps sinensis into mice can enhance the activity of T cell acid esterase, spleen weight, nucleic acid and protein content in the spleen, and increase the formation rate of T-cell E-rosette in the spleen; It can also antagonize the decrease of spleen weight and E-rosette formation caused by prednisolone and cyclophosphamide. Cordyceps sinensis or Cordyceps sinensis can also increase the serum immunoglobulin G of normal, yang deficiency and yin deficiency mice.

3. Impact on endocrine

The aqueous extracts of Cordyceps sinensis and Cordyceps sinensis can increase the seminal vesicles of castrated young male rats, showing androgen like effects; Cordyceps sinensis and water extract of Cordyceps sinensis could increase the content of plasma cortisol in male mice by gavage; It can also increase the content of adrenal cholesterol and make adrenal gland gain weight; Cordyceps sinensis has androgen like effects and has preventive and therapeutic effects on "Yang deficiency like" mice caused by hydrocortisone acetate.

4. Effect on renal function

In clinical practice, the preparation of artificial Cordyceps sinensis is applied to patients with chronic nephritis. The results show that it can reduce the proteinuria of nephritis, increase the serum zinc content, reduce the copper/zinc ratio, and make hematuria significantly improved.

5. Anti inflammatory effect

Cordyceps sinensis or Cordyceps fungus liquid was injected subcutaneously or intraperitoneally to inhibit croton oil or xylene induced ear edema in mice, egg white or formaldehyde induced paw edema and cotton ball granuloma in rats. The anti-inflammatory effect is related to its ability to enhance the synthesis and secretion of adrenocortical hormones.

6. Anti tumor effect

The water and alcohol extracts of Cordyceps sinensis can inhibit the growth of S180 sarcoma, Lewis lung cancer and mA-737 breast cancer in mice; The mycelia had significant inhibitory effects on S180, S37, EcA and P388 of mice; The aqueous extracts of Cordyceps sinensis and Cordyceps sinensis can not only inhibit the growth of S180 tumor in mice, but also enhance the anti-tumor effect of cyclophosphamide.

7. Anti aging effect

Cordyceps sinensis extract can increase the activity of age-related enzymes (such as SOD, GSH Px, catalase), and reduce the activity of lipid peroxidation and monoamine oxidase in aging mice; Cordyceps sinensis extract can enhance brain function and antioxidant enzyme activity of aging mice induced by D-galactose. The induction of steroid hormone synthesis of Cordyceps sinensis is related to its anti-aging function.

8. Effect on respiratory system

The aqueous extract of Cordyceps sinensis can significantly enhance the secretion of adrenaline, relax bronchial smooth muscle, dilate the bronchus, expel phlegm, and relieve asthma. It has good therapeutic effects on cough, sputum and blood, pulmonary tuberculosis, chronic bronchitis and other diseases.

9. Other functions

① Sedative effect; ② Antiasthmatic effect; ③ Anti cancer effect; ④ Exciting the isolated ileum of guinea pigs; ⑤ Increase the blood sugar of hungry mice; ⑥ Anti fatigue, prolonging the swimming time of hungry mice; ⑦ It has inhibitory effect on mycobacterium tuberculosis, pneumococcus and streptococcus; ⑧ It can reduce the death caused by coliform endotoxin; ⑨ Anti nicotine and anti salivation effects.


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