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Glutathione is a tripeptide containing γ-amide bond and sulfhydryl group, composed of glutamic acid, cysteine and glycine, present in almost every cell of the body. Glutathione can help maintain normal immune system function, and has antioxidant and integrated detoxification effects. The sulfhydryl group on cysteine is its active group (so it is often abbreviated as G-SH), which is easy to combine with certain drugs and toxins, so that it has an integrated detoxification effect. Glutathione can not only be used in medicine, but also can be used as the base material of functional food, which is widely used in functional food such as delaying aging, enhancing immunity, and anti-tumor.
Glutathione has two forms, reduced (G-SH) and oxidized (G-S-S-G), and reduced glutathione accounts for the vast majority under physiological conditions. Glutathione reductase can catalyze the interconversion between the two types, and the coenzyme of this enzyme can also provide NADPH for the pentose phosphate bypass metabolism.
1. Detoxification: combine with poison or drug to eliminate its toxic effect;
2. Participate in redox reactions: As an important reducing agent, it participates in various redox reactions in the body;
3. Protect the activity of thiol enzymes: keep the active group of thiol enzymes—SH in a reduced state;
4. Maintain the stability of the membrane structure of red blood cells: eliminate the destructive effect of oxidants on the membrane structure of red blood cells.
1. Clinical drugs
Glutathione drugs are widely used in clinical applications. In addition to using its sulfhydryl group to chelate heavy metals, fluoride, mustard gas, and other toxins for poisoning, they are also used in hepatitis, hemolytic diseases, as well as keratitis, cataract, and retinal diseases, as therapeutic or adjuvant drugs. In recent years, Western scientists, especially Japanese scholars, have found that glutathione has the function of inhibiting HIV.
The latest research also shows that GSH can correct the imbalance of acetylcholine and cholinesterase, play an anti allergic role, also prevent skin aging and pigmentation, reduce the formation of melanin, improve skin antioxidant capacity, and make the skin shiny. In addition, GSH has a good role in treating eye corner membrane disease and improving sexual function.
2. Antioxidant effect
As an important antioxidant in the body, glutathione can eliminate free radicals in the body; Because GSH itself is susceptible to oxidation by certain substances, it can protect the sulfhydryl groups in many molecules such as proteins and enzymes from being oxidized by harmful substances in the body, thereby ensuring the normal functioning of molecular physiological functions such as proteins and enzymes; There are many levels of glutathione in human red blood cells, which is of great significance in protecting the sulfhydryl group of proteins on the red blood cell membrane from being reduced and preventing hemolysis.
3. Food Additives
When added to flour products, it can play a reducing role. It not only shortens the time for making bread by half or one-third of the original time, greatly improves labor conditions, and plays a role in strengthening food nutrition and other functions.
When added to yogurt and infant foods, it is equivalent to vitamin C and can act as a stabilizer.
Mixing it into the fish cake can prevent the color from deepening.
When added to foods such as meat products and cheese, it has the effect of enhancing flavor.
Glutathione is a tripeptide containing γ-amide bond and sulfhydryl group, composed of glutamic acid, cysteine and glycine, present in almost every cell of the body. Glutathione can help maintain normal immune system function, and has antioxidant and integrated detoxification effects. The sulfhydryl group on cysteine is its active group (so it is often abbreviated as G-SH), which is easy to combine with certain drugs and toxins, so that it has an integrated detoxification effect. Glutathione can not only be used in medicine, but also can be used as the base material of functional food, which is widely used in functional food such as delaying aging, enhancing immunity, and anti-tumor.
Glutathione has two forms, reduced (G-SH) and oxidized (G-S-S-G), and reduced glutathione accounts for the vast majority under physiological conditions. Glutathione reductase can catalyze the interconversion between the two types, and the coenzyme of this enzyme can also provide NADPH for the pentose phosphate bypass metabolism.
1. Detoxification: combine with poison or drug to eliminate its toxic effect;
2. Participate in redox reactions: As an important reducing agent, it participates in various redox reactions in the body;
3. Protect the activity of thiol enzymes: keep the active group of thiol enzymes—SH in a reduced state;
4. Maintain the stability of the membrane structure of red blood cells: eliminate the destructive effect of oxidants on the membrane structure of red blood cells.
1. Clinical drugs
Glutathione drugs are widely used in clinical applications. In addition to using its sulfhydryl group to chelate heavy metals, fluoride, mustard gas, and other toxins for poisoning, they are also used in hepatitis, hemolytic diseases, as well as keratitis, cataract, and retinal diseases, as therapeutic or adjuvant drugs. In recent years, Western scientists, especially Japanese scholars, have found that glutathione has the function of inhibiting HIV.
The latest research also shows that GSH can correct the imbalance of acetylcholine and cholinesterase, play an anti allergic role, also prevent skin aging and pigmentation, reduce the formation of melanin, improve skin antioxidant capacity, and make the skin shiny. In addition, GSH has a good role in treating eye corner membrane disease and improving sexual function.
2. Antioxidant effect
As an important antioxidant in the body, glutathione can eliminate free radicals in the body; Because GSH itself is susceptible to oxidation by certain substances, it can protect the sulfhydryl groups in many molecules such as proteins and enzymes from being oxidized by harmful substances in the body, thereby ensuring the normal functioning of molecular physiological functions such as proteins and enzymes; There are many levels of glutathione in human red blood cells, which is of great significance in protecting the sulfhydryl group of proteins on the red blood cell membrane from being reduced and preventing hemolysis.
3. Food Additives
When added to flour products, it can play a reducing role. It not only shortens the time for making bread by half or one-third of the original time, greatly improves labor conditions, and plays a role in strengthening food nutrition and other functions.
When added to yogurt and infant foods, it is equivalent to vitamin C and can act as a stabilizer.
Mixing it into the fish cake can prevent the color from deepening.
When added to foods such as meat products and cheese, it has the effect of enhancing flavor.
