Dextrin (pharmaceutical excipients)
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Dextrin (pharmaceutical excipients)

Product name: Dextrin (pharmaceutical excipients)
CAS No.: 9004-53-9
Molecular Formula: C18H32O16
Specification: 25kg
Appearance: White, yellow or brown liquid powder
Storage: Sealed storage

Dextrin pharmaceutical excipients description

Dextrin is a cyclic oligosaccharide compound. Dextrins can be prepared by heating starch in the dry state with or without the aid of appropriate acids and buffers to incompletely hydrolyze the starch; moisture can be passed through during the heating process. phEur 2002 contains that dextrins are derived from corn (maize) or potato starch. Dextrin is generally considered to be non-toxic and non-irritating at the doses applied as an excipient.

Pharmaceutical dextrin function and application

1. Dextrin can be used as a suspension aid; binder for tablets; diluent for tablets and capsules.

2. Dextrin is a polymer of glucose and is used as an adhesive and hardener for surgical dressings.

3. Dextrin is used as diluent for tablets and capsules; binder for tablet granules.

4. Dextrin is used as a sugar source for people with special nutritional needs due to its low electrolyte content and its absence of lactose and sucrose.

5. Dextrins are also used in cosmetics.

Dextrin effect

Dextrin is an intermediate product of starch decomposition. Its chemical formula is (C6H10O5) n, which is the same as that of starch, but its degree of polymerization is between soluble starch and maltose. It turns red when it meets iodine. Dextrin with low degree of polymerization does not have color reaction.

Dextrins are divided into yellow dextrins and white dextrins. The dextrin obtained by direct roasting is commonly known as "British gum", also known as calcined dextrin, which is brown. Acid roasting can decompose at lower temperature. The color of the product is generally light yellow or white, called white dextrin.

The main purpose of dextrin is to serve as an adhesive. In warp sizing, dextrin can be used as an additive to starch. The purpose is to reduce the viscosity of starch and improve the permeability of the size. The starch paste added with dextrin is easy to desize, but the adhesion is poor, and the size film is brittle and hard. It is often mixed with PVA and used for sizing viscose yarn and cuprammonia filament. It is not easy to fuzz during yarn separation. After synthetic sizing and modified starch are widely used, dextrin is rarely used in the formula of warp sizing.