Ganoderma Extract
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Ganoderma Extract

Product Name:Ganoderma extract
Alias: Ganoderma lucidum extract
CAS NO.:223751-82-4
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Ganoderma lucidum introduction

Ganoderma lucidum is called "immortal mushroom" in China and has been used in Oriental medicine for more than 2000 years. In recent years, its active ingredients have become the subject of in-depth research, mainly focusing on its obvious prevention or treatment of certain cancers, its help in the treatment of liver disease, HIV infection, acute or periodic herpesvirus infection, hypertension, chronic bronchitis, allergy and asthma, and its ability to benign regulate immune function. Ganoderma lucidum mainly grows on decayed wood or stumps in the wild of China's coastal provinces. Its fruiting body is mainly used for medicine.

Ganoderma lucidum extract

Ganoderma lucidum extract is extracted by fermentation of Ganoderma lucidum, and the main components are Ganoderma lucidum triterpenoids and Ganoderma lucidum polysaccharides.

Ganoderma extract powder medical efficacy

1. Anti cancer activity

Cancer studies in animals (e.g. rat connective tissue cancer model) showed that there was a 50% tumor regression rate after treatment with Ganoderma lucidum extract. Ganoderma lucidum extract has been used by some Japanese surgeons to treat cancer patients, and its remarkable anti-tumor and immunostimulatory effects have been noted in many cases. Polysaccharides isolated from Ganoderma lucidum and other medicinal mushrooms have been patented in Japan as immunomodulators in cancer treatment. It is mixed with chemical or radiation therapy and shows the ability to reduce side effects, improve therapeutic effects, and it is used to promote disease recovery.

Chinese research shows that Ganoderma lucidum extract enhances the anti-tumor ability of macrophages and T-cells. Ganoderma lucidum extract is known to have other immunomodulatory effects and antioxidant properties. Animal studies also showed that the polysaccharide part of Ganoderma lucidum can induce apoptosis of leukemia cells (programmed death of cancer cells) and induce 40% - 45% of leukemia cells to differentiate when treated with Ganoderma lucidum polysaccharide, proving its obvious cancer treatment potential. These effects are mainly due to the increased secretion of anti-tumor cytokines (signal agents) induced by Ganoderma lucidum polysaccharides, namely TNF alpha and IFN gamma, and these two cytokines show synergistic effects in inhibiting the growth of leukemia cells. In a related experiment, the D-glucan polysaccharide part of Ganoderma lucidum showed a dramatic tumor recession in the study of rat malignant tumors. In many experimental animals, the selected population experienced a complete tumor regression 5 weeks after injection of beta D-glucan polysaccharide. The experiment carried out by Y. Song et al. reported that 90% of the tumor inhibition rate and 75% of the tumor recession in the diseased animals.

2. Improve immune system

Ganoderma lucidum extract can regulate many components of the immune system, some of which are considered to have obvious anti-tumor properties. In an experiment involving 2000 cases in China, the treatment of senile chronic bronchitis with concentrated Ganoderma lucidum products showed a good response. The study showed a success rate of more than 60%. After several months of treatment, the level of immunoglobulin A in sputum increased significantly. Immunoglobulin A is the main immunoglobulin found in the respiratory tract. It is generally deficient in nasal allergy, systemic lupus and rheumatoid arthritis. Ganoderma lucidum extract supplements have been shown to improve asthma and nasal allergy symptoms. The two important components of ganoderma lucidum extract, oleic acid and cyclopentasulfide, have shown that they can inhibit the release of histamine, which may be the reason why they are beneficial to asthma. At the same time, a special protein binding polysaccharide in ganoderma lucidum extract, called Glhw-02, has shown effective antiviral properties against type 1 and type 2 simple viruses under laboratory conditions. A small-scale human experiment showed that Ganoderma lucidum extract "dramatically" reduced the pain of two patients with post herpetic neuralgia and the severe pain of two patients with herpes zoster infection (herpes zoster, caused by herpes virus).

Under laboratory conditions, various ganoderic acids and polysaccharides in the extract of Ganoderma lucidum show that they can be used as active anti HIV substances, and show the ability to reduce virus replication by 50% at a conservative dose. After being mixed with other oriental herbs, Ganoderma lucidum is used to treat AIDS related syndrome and AIDS, and to treat chronic fatigue syndrome alone or in combination with other medicinal materials.

3. Cardiovascular health

Two controlled human experiments showed that Ganoderma lucidum extract can reduce hypertension to a very significant extent (systolic and diastolic heart pressure), even for those patients who had previously failed to respond to known antihypertensive drugs. Animal experiments showed that Ganoderma lucidum extract could reduce blood pressure through central inhibition of sympathetic nerve activity, although this effect basically did not slow down the heart rate or lead to sedative effect. In the laboratory environment, Ganoderma lucidum extract has a slight to moderate effect of less platelet accumulation, which may help reduce the risk of cardiovascular disease in the future. It also shows that it can increase endurance, blood flow into the brain and improve cell oxygenation. Similarly, it contributes to energy synthesis at the cellular level. It may improve cardiovascular health and be used in some cultures to improve memory and intelligence, including the successful application in the study of Alzheimer's patients.

4. Liver protection

Ganoderma lucidum is used as a prescription drug for the treatment of chronic and acute hepatitis in China. Polysaccharides from Ganoderma lucidum have strong anti hepatotoxin properties, and they have shown the liver protection effect under chemical induced injury in the laboratory environment, including the protection of highly toxic and lethal substance carbon tetrachloride.

5. Support the nervous system

Ganoderma lucidum is traditionally recommended by Chinese and Japanese herbalists for insomnia due to its "sleep promoting factor". Long term use will lead to obvious promotion of slow wave sleep. Ganoderma lucidum is used as a prescription drug for many psychiatric and neurological problems in China, including muscle diseases, anorexia and debilitation after long-term diseases.

6. Anti allergic/anti-inflammatory effects

In the 1970s and 1980s, the antiallergic effect of Ganoderma lucidum became the subject of ongoing research in China and Japan. Studies have shown that Ganoderma lucidum extract significantly inhibits all four types of allergic reactions, including positive effects on asthma and contact dermatitis. In 1990, scientists at the University of Texas Health Science Center in San Antonio found that Ganoderma lucidum can be effectively used to treat neck stiffness, shoulder stiffness, conjunctivitis (inflammation occurs in the middle membranes of eyes and eyelids), bronchitis, rheumatism and improve the immune system without obvious side effects.

The anti inflammation ability of Ganoderma lucidum may be partly due to its free radical scavenging ability. Ganoderma lucidum extract can significantly enhance the free radical scavenging ability of blood, especially against the significantly harmful hydroxyl free radicals. The hydroxyl radical scavenging capacity of Ganoderma lucidum is so strong that its scavenging effect continues after the Ganoderma lucidum extract is absorbed and metabolized.

7. Anti aging

The ancient Chinese medical classics Shennong Herbal Scripture records that Ganoderma lucidum can effectively enhance life energy (Qi), increase thinking ability and prevent amnesia. It can restore the body and intelligence, delay aging and enable human beings to extend life.


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