 |
| Quantity: | |
|---|---|
Glutathione is a tripeptide containing γ-amide bond and sulfhydryl group, composed of glutamic acid, cysteine and glycine, present in almost every cell of the body.
Glutathione can help maintain normal immune system function, and has antioxidant and integrated detoxification effects. The sulfhydryl group on cysteine is its active group (so it is often abbreviated as G-SH), which is easy to combine with certain drugs and toxins, so that it has an integrated detoxification effect. Glutathione can not only be used in medicine, but also can be used as the base material of functional food, which is widely used in functional food such as delaying aging, enhancing immunity, and anti-tumor.
Glutathione has two forms, reduced (G-SH) and oxidized (G-S-S-G), and reduced glutathione accounts for the vast majority under physiological conditions. Glutathione reductase can catalyze the interconversion between the two types, and the coenzyme of this enzyme can also provide NADPH for the pentose phosphate bypass metabolism.
1. Detoxification: Combine with poison or drug to eliminate its toxic effect.
2. Participate in redox reactions: As an important reducing agent, it participates in various redox reactions in the body.
3. Protect the activity of thiol enzymes: keep the active group of thiol enzymes—SH in a reduced state.
4. Maintain the stability of the membrane structure of red blood cells: eliminate the destructive effect of oxidants on the membrane structure of red blood cells.
1. Clinical drugs
Glutathione drugs are widely used in clinic. In addition to using its sulfhydryl group to chelate heavy metals, fluoride, mustard gas and other toxins poisoning, they are also used in hepatitis, hemolytic diseases, keratitis, cataract and retinal diseases as therapeutic or adjuvant drugs. In recent years, Western scientists, especially Japanese scholars, have found that glutathione has the function of inhibiting HIV.
The latest research also shows that GSH can correct the imbalance of acetylcholine and cholinesterase, play an anti-allergic role, prevent skin aging and pigmentation, reduce the formation of melanin, improve skin antioxidant capacity and make skin shiny. In addition, GSH also has a very good role in the treatment of keratosis and improvement of sexual function.
2. Antioxidant effect
As an important antioxidant in the body, glutathione can eliminate free radicals in the body; Because GSH itself is easily oxidized by some substances, it can protect the sulfhydryl groups in many proteins and enzymes from being oxidized by harmful substances in the body, thus ensuring the normal functioning of proteins and enzymes and other molecular physiological functions; There is a lot of glutathione in human red blood cells, which is of great significance to protect the sulfhydryl group of protein on the red blood cell membrane from being reduced and prevent hemolysis.
3. Food additives
1. It can play a reducing role when added to flour products. It not only shortened the time of making bread to half or one third of the original time, but also greatly improved the working conditions, and played a role in strengthening food nutrition and other functions.
2. When it is added to yogurt and infant food, it is equivalent to vitamin C, which can play the role of stabilizer.
3. Mix it into the fish cake to prevent the color from deepening.
4. When added to meat products, cheese and other foods, it has the effect of strengthening flavor.
Glutathione is a tripeptide containing γ-amide bond and sulfhydryl group, composed of glutamic acid, cysteine and glycine, present in almost every cell of the body.
Glutathione can help maintain normal immune system function, and has antioxidant and integrated detoxification effects. The sulfhydryl group on cysteine is its active group (so it is often abbreviated as G-SH), which is easy to combine with certain drugs and toxins, so that it has an integrated detoxification effect. Glutathione can not only be used in medicine, but also can be used as the base material of functional food, which is widely used in functional food such as delaying aging, enhancing immunity, and anti-tumor.
Glutathione has two forms, reduced (G-SH) and oxidized (G-S-S-G), and reduced glutathione accounts for the vast majority under physiological conditions. Glutathione reductase can catalyze the interconversion between the two types, and the coenzyme of this enzyme can also provide NADPH for the pentose phosphate bypass metabolism.
1. Detoxification: Combine with poison or drug to eliminate its toxic effect.
2. Participate in redox reactions: As an important reducing agent, it participates in various redox reactions in the body.
3. Protect the activity of thiol enzymes: keep the active group of thiol enzymes—SH in a reduced state.
4. Maintain the stability of the membrane structure of red blood cells: eliminate the destructive effect of oxidants on the membrane structure of red blood cells.
1. Clinical drugs
Glutathione drugs are widely used in clinic. In addition to using its sulfhydryl group to chelate heavy metals, fluoride, mustard gas and other toxins poisoning, they are also used in hepatitis, hemolytic diseases, keratitis, cataract and retinal diseases as therapeutic or adjuvant drugs. In recent years, Western scientists, especially Japanese scholars, have found that glutathione has the function of inhibiting HIV.
The latest research also shows that GSH can correct the imbalance of acetylcholine and cholinesterase, play an anti-allergic role, prevent skin aging and pigmentation, reduce the formation of melanin, improve skin antioxidant capacity and make skin shiny. In addition, GSH also has a very good role in the treatment of keratosis and improvement of sexual function.
2. Antioxidant effect
As an important antioxidant in the body, glutathione can eliminate free radicals in the body; Because GSH itself is easily oxidized by some substances, it can protect the sulfhydryl groups in many proteins and enzymes from being oxidized by harmful substances in the body, thus ensuring the normal functioning of proteins and enzymes and other molecular physiological functions; There is a lot of glutathione in human red blood cells, which is of great significance to protect the sulfhydryl group of protein on the red blood cell membrane from being reduced and prevent hemolysis.
3. Food additives
1. It can play a reducing role when added to flour products. It not only shortened the time of making bread to half or one third of the original time, but also greatly improved the working conditions, and played a role in strengthening food nutrition and other functions.
2. When it is added to yogurt and infant food, it is equivalent to vitamin C, which can play the role of stabilizer.
3. Mix it into the fish cake to prevent the color from deepening.
4. When added to meat products, cheese and other foods, it has the effect of strengthening flavor.
