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Naringin is a flavanone-7-O-glycoside between the flavanone naringenin and the disaccharide neohesperidose. The flavonoid naringin occurs naturally in citrus fruits, especially in grapefruit, where naringin is responsible for the fruit's bitter taste. In commercial grapefruit juice production, the enzyme naringinase can be used to remove the bitterness created by naringin. In humans naringin is metabolized to the aglycone naringenin (not bitter) by naringinase present in the gut.
Naringin is a complex of glucose, rhamnose and grapefruit ligand. It is white to light yellow crystalline powder. Naringin tastes bitter, and 20mg / kg aqueous solution still has a bitter taste. Slightly soluble in water, easily soluble in hot water, ethanol, acetone and warm glacial acetic acid.
pharmacological action
Naringin has anti-inflammatory, anti-virus, anti-cancer, anti mutation, anti-allergy, anti-ulcer, analgesic and anti hypertension activities. It can reduce blood cholesterol, reduce thrombosis, improve local microcirculation and nutrient supply. It can be used to prevent and treat cardiovascular and cerebrovascular diseases in production.
(1) Antibacterial: the effect on Staphylococcus aureus, Escherichia coli, dysentery bacillus and typhoid bacillus is weaker than its aglycone.
(2) Anti inflammatory
(3) Antiviral
(4) Inhibition of ocular aldose reductase: this effect may contribute to the treatment of diabetes induced cataract.
(5) As a bitter
(6) It can be used as raw material for the synthesis of neohesperidin and neohesperidin dihydrochalcone
Dietotherapy
1. Antibacterial and antiviral
Naringin and hesperidin can inhibit the growth of Staphylococcus aureus, Escherichia coli, dysentery bacillus and typhoid bacillus in test tube. Naringin can inhibit yeast and fungi, and prevent and protect mice infected with virus. Naringin and hesperidin in grapefruit are similar to other flavonoids and have anti-inflammatory effects.
2. Reduce blood sugar
The fresh grapefruit juice contains insulin-like components, which can reduce blood sugar. It is a good food for patients with diabetes and obesity.
3. Spasmolysis and enhancement of vitamin C
Naringin contained in grapefruit has obvious antispasmodic effect. Naringin and hesperidin can improve the blood cell aggregation in the blood vessels of ocular bulbar conjunctiva and the decrease of capillary resistance caused by vitamin C deficiency in mice.
4. Expectorant and antitussive
The outer peel of grapefruit is orange red, which is a commonly used traditional Chinese medicine. The limonene and paiene contained therein, after inhalation, can make the respiratory tract secretions become variable and dilute, which is conducive to the discharge of sputum. It has a good expectorant and antitussive effect. It is a good product for the treatment of chronic cough and asthma and cold deficiency phlegm and asthma in the elderly.
It is also known as the ripe grapefruit, grapefruit and grapefruit trees. Fresh grapefruit contains insulin like, naringin, neohesperidin, volatile oil, vitamin B1, vitamin B2, niacin, vitamin C, fructose, glucose, protein, lipids, iron, calcium, phosphorus and crude fiber.
Naringin is a flavanone-7-O-glycoside between the flavanone naringenin and the disaccharide neohesperidose. The flavonoid naringin occurs naturally in citrus fruits, especially in grapefruit, where naringin is responsible for the fruit's bitter taste. In commercial grapefruit juice production, the enzyme naringinase can be used to remove the bitterness created by naringin. In humans naringin is metabolized to the aglycone naringenin (not bitter) by naringinase present in the gut.
Naringin is a complex of glucose, rhamnose and grapefruit ligand. It is white to light yellow crystalline powder. Naringin tastes bitter, and 20mg / kg aqueous solution still has a bitter taste. Slightly soluble in water, easily soluble in hot water, ethanol, acetone and warm glacial acetic acid.
pharmacological action
Naringin has anti-inflammatory, anti-virus, anti-cancer, anti mutation, anti-allergy, anti-ulcer, analgesic and anti hypertension activities. It can reduce blood cholesterol, reduce thrombosis, improve local microcirculation and nutrient supply. It can be used to prevent and treat cardiovascular and cerebrovascular diseases in production.
(1) Antibacterial: the effect on Staphylococcus aureus, Escherichia coli, dysentery bacillus and typhoid bacillus is weaker than its aglycone.
(2) Anti inflammatory
(3) Antiviral
(4) Inhibition of ocular aldose reductase: this effect may contribute to the treatment of diabetes induced cataract.
(5) As a bitter
(6) It can be used as raw material for the synthesis of neohesperidin and neohesperidin dihydrochalcone
Dietotherapy
1. Antibacterial and antiviral
Naringin and hesperidin can inhibit the growth of Staphylococcus aureus, Escherichia coli, dysentery bacillus and typhoid bacillus in test tube. Naringin can inhibit yeast and fungi, and prevent and protect mice infected with virus. Naringin and hesperidin in grapefruit are similar to other flavonoids and have anti-inflammatory effects.
2. Reduce blood sugar
The fresh grapefruit juice contains insulin-like components, which can reduce blood sugar. It is a good food for patients with diabetes and obesity.
3. Spasmolysis and enhancement of vitamin C
Naringin contained in grapefruit has obvious antispasmodic effect. Naringin and hesperidin can improve the blood cell aggregation in the blood vessels of ocular bulbar conjunctiva and the decrease of capillary resistance caused by vitamin C deficiency in mice.
4. Expectorant and antitussive
The outer peel of grapefruit is orange red, which is a commonly used traditional Chinese medicine. The limonene and paiene contained therein, after inhalation, can make the respiratory tract secretions become variable and dilute, which is conducive to the discharge of sputum. It has a good expectorant and antitussive effect. It is a good product for the treatment of chronic cough and asthma and cold deficiency phlegm and asthma in the elderly.
It is also known as the ripe grapefruit, grapefruit and grapefruit trees. Fresh grapefruit contains insulin like, naringin, neohesperidin, volatile oil, vitamin B1, vitamin B2, niacin, vitamin C, fructose, glucose, protein, lipids, iron, calcium, phosphorus and crude fiber.
