Pharmaceutical Grade Povidone K30
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Pharmaceutical Grade Povidone K30

Product Name:Pharmaceutical grade povidone K30
Molecular formula:(C6H9NO)n
Appearance:White to milky white powder

Povidone k30 usual dosage and maximum dosage

The WHO tentatively set the daily intake of povidone at 25 mg per kilogram of body weight. The maximum dosage for eye use is 2.00%, the maximum dosage for oral capsules is 30.00 mg, and the maximum dosage for oral tablets is 55.00 mg.

Povidone k30 stability and Storage Conditions

Povidone becomes darker when heated to 150°C, and its water solubility decreases. At 110~130℃, it is stable for a short time; the properties of the aqueous solution are not changed by steam sterilization. It is easy to grow mold in the aqueous solution, and it is necessary to add antibacterial preservatives. Povidone is stored under normal conditions and it does not decompose or degrade. However, due to the strong hygroscopicity of the powder, povidone should be stored in an airtight container in a cool, dry environment.

Povidone k30 function

Povidone is widely used in pharmaceuticals, mainly in solid preparations. In tablets, the povidone solution acts as a binder in wet granulation. Povidone powder can also be directly added to other powders in dry state and mixed, and then granulated by adding water, alcohol or hydroalcoholic solution. In oral or parenteral administration, povidone acts as a solubilizer to accelerate the dissolution of poorly soluble drugs from solid dosage forms. Povidone solutions can also be used as coating materials. In addition, povidone acts as a suspending agent, stabilizer, or viscosity-increasing agent in some topical and oral suspensions and solutions. Many poorly soluble drugs are mixed with povidone and their solubility increases.

Povidone k30 incompatibility

Povidone is compatible with many substances in solution, such as inorganic salts, natural or synthetic resins, and other chemicals. But it is easy to form molecular adducts with compounds such as sulfathiazole, sodium salicylate, salicylic acid, phenobarbital, and tannic acid in solution. Some bacteriostatic preservatives, such as thimerosal, it can form complexes with povidone, thereby reducing their bacteriostatic effect.