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Product Name:Phosphatidylserine
CAS NO.:51446-62-9
Molecular formula:C42H82NO10P
Molecular weight:792.07
Storage condition:under inert gas (nitrogen or Argon) at 2–8 °C

Phosphatidylserine introduction

Phosphatidylsserine, also known as serine phospholipid, diacylglyceryl phosphoserine, or PS for short, it is a kind of ubiquitous phospholipid, usually located in the inner layer of cell membrane. Glycerophosphate esters in phosphate compounds are one of the components of cell membrane, and are related to a series of membrane functions. Especially in the human nervous system, it is one of the important components of the cell membrane of the brain, and plays an important role in regulating various functions of the brain (especially memory and emotional stability of the brain). For example, it can affect the fluidity and permeability of the cell membrane, and can activate the metabolism and synthesis of a variety of enzymes. For example, there are phosphatidylcholine (19%), sphingomyelin (8%), phosphatidylethanolamine (16%) and phosphatidylserine (10%) on the human erythrocyte membrane. And only the latter has a net negative charge on the cell membrane, which contributes to the asymmetry of the membrane. It can also activate the damaged surface prothrombin. It can be transformed with phosphatidylcholine and phosphatidylethanolamine in vivo. Due to the difference between R1 and R2, phosphatidylserine has actually become the general name of a class of compounds.

Phosphatidylserine Main efficacy

1. It can help the cell wall to maintain flexibility, and can enhance the efficiency of neurotransmitters that transmit brain signals, help the brain to operate efficiently, and stimulate the activation of the brain. At the earliest time, phosphatidylserine was used to prevent middle and old aged dementia. In recent years, with the advancement of memory clinical experiments, the application objects of phosphatidylserine are gradually younger. In a recent Israeli study, it was found that the volunteers who took phosphatidylserine supplements had significantly increased memory cognition, memory review and thinking flexibility. The ability to learn and recall immediately improved significantly. In China, the Nutrition and Food Safety Research Center of the Third Military Medical University conducted a clinical study on 120 senior three candidates. Before and after the trial, the subjects were scored on their memory by using the standard method of the Clinical Memory Scale. The subscale included directed memory, associative learning, free image recall, meaningless figure recognition, and portrait feature association recall. The results showed that phosphatidylserine could significantly improve students' memory, and some memory indexes could be improved by more than 20% in a short time.

2. It can safely enhance memory in the short term. Supplementing phosphatidylserine can increase the number of brain spikes, the fluidity of brain cell membrane, and promote glucose metabolism in brain cells, thus making brain cells more active, promoting concentration, alertness and memory;

3. Phosphatidyl serine (PS) can also help alleviate brain fatigue and repair brain cell damage. Because of this special function, phosphatidylserine related nutritional supplements are widely used in nutritional supplements before examination.

Phosphatidylserine Intake pathway

Phosphatidylsserine is a naturally occurring ingredient in foods and also in human milk. Both meat and fish contain phosphatidylserine, and the content in brain or viscera (such as liver and kidney) is high. The content of phosphatidylserine in dairy products and vegetables (excluding beans) is very low.

The change of modern people's eating habits (such as no longer eating viscera), the increased awareness of eating healthy food (such as eating low-fat, low cholesterol food and avoiding eating a lot of meat food), and the food crisis (such as mad cow disease and foot and mouth disease) have led to less and less phosphatidylserine intake. More seriously, the content of natural phospholipids in lipids and oil products produced by modern industrialization has decreased, further reducing the amount of phosphatidylserine that normal people should ingest every day. Generally speaking, if there are more meat and fish in the diet, the intake of phosphatidylserine is about 180 mg/day; If the fat content in the food is low, the daily intake of phosphatidylserine will be only 100 mg, or even less than 50 mg. According to statistics, the difference between the daily intake of phosphatidylserine in normal people and the normal demand is 70-150 mg, especially in vegetarians, with the difference reaching 200-250 mg. In view of the above reasons, normal people need to supplement 100-300 mg of pure phosphatidylserine every day, which is more important for vegetarians, people who eat low fat or low cholesterol diets and the elderly. In addition, other dietary habits can also reduce the content of phosphatidylserine in the brain. For example, the lack of omega 3 fatty acids in the diet will reduce the content of phosphatidylserine in the brain by 28%, thereby changing the biochemical function of the hippocampus.