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Poria cocos extract comes from the dried sclerotia of Poria cocos, a fungus of the family Poriaceae. Poria is an annual or perennial fungus. The ancient name is Fuling, Fu Rabbit. It is also known as Songshu, Songling, Songbai taro, etc. Take sclerotia as medicine. It is mainly produced in Hebei, Henan, Shandong, Anhui, Zhejiang and other places. The main components of Poria cocos extract are triterpenoids and polysaccharides, which have the effects of invigorating the spleen, calming the nerves, promoting diuresis, and infiltrating dampness. It is used for the treatment of spleen deficiency with little food, edema and urine. Modern pharmacological studies have shown that Poria cocos has many pharmacological effects, such as inhibiting the growth of splenic tumors, enhancing the body's immunity, etc.
Poria cocos contains polysaccharides, triterpenoids and fatty acids. Pachymose is the main component, with the content of 84.2%. Other reports β- Pachyman（ β- Pachyman) is the main component, accounting for 93% of the dry product. Triterpenoids include pachymic acid, humic acid, clofibric acid, odontogenic acid, abietic acid, and abietic acid. Fatty acids include caprylic acid and lauric acid. Other ingredients include ergosterol, gum, chitin, protein, fat, lecithin, etc.
1. Diuretic and detumescence effect
Lingsu is a new aldosterone receptor antagonist, which is beneficial to urine excretion, recovery of renal function and elimination of protein.
2. Effect on digestive system
The triterpenoids of Poria cocos enhanced the differentiation inducing activity of insulin, and the triterpenoids themselves also had differentiation inducing activity. Poria triterpenoids and their derivatives can inhibit vomit induced by oral copper sulfate in frogs.
3. Stone prevention
Poria cocos polysaccharide can effectively inhibit the formation and deposition of calcium oxalate crystals in the kidney of rats, and has a good anti stone effect.
4. Anti rejection effect
Poria cocos extract can obviously inhibit the acute rejection of heterotopic heart transplantation in rats.
5. Antibacterial and antiviral effects
100% filter paper of Poria cocos extract can inhibit Staphylococcus aureus, Staphylococcus albus, Pseudomonas aeruginosa, Bacillus anthracis, Escherichia coli, Streptococcus A and Streptococcus B.
6. Anticonvulsant effect
The total triterpenoids of Poria cocos can resist the maximum electric shock and pentylenetetrazole convulsions to varying degrees, which proves that the total triterpenoids of Poria cocos have obvious anticonvulsant effects.
7. Anti inflammatory effect
The total triterpenoids of Poria cocos can inhibit the acute inflammation such as auricle swelling in mice caused by xylene and the permeability of abdominal capillaries in mice, and also have a strong inhibitory effect on the subacute inflammation of cotton ball granuloma in rats. It shows that the total triterpenoids of Poria cocos is one of the main effective components of the anti-inflammatory effect of Poria cocos, and its mechanism may be related to the inhibition of phospholipase A2 activity by the triterpenoids contained in Poria cocos.
8. Whitening effect
White Poria cocos has significant inhibition on tyrosinase and is a competitive inhibition. Reducing melanin production by inhibiting tyrosinase activity may be one of the mechanisms of whitening traditional Chinese medicine.
Poria cocos extract comes from the dried sclerotia of Poria cocos, a fungus of the family Poriaceae. Poria is an annual or perennial fungus. The ancient name is Fuling, Fu Rabbit. It is also known as Songshu, Songling, Songbai taro, etc. Take sclerotia as medicine. It is mainly produced in Hebei, Henan, Shandong, Anhui, Zhejiang and other places. The main components of Poria cocos extract are triterpenoids and polysaccharides, which have the effects of invigorating the spleen, calming the nerves, promoting diuresis, and infiltrating dampness. It is used for the treatment of spleen deficiency with little food, edema and urine. Modern pharmacological studies have shown that Poria cocos has many pharmacological effects, such as inhibiting the growth of splenic tumors, enhancing the body's immunity, etc.
Poria cocos contains polysaccharides, triterpenoids and fatty acids. Pachymose is the main component, with the content of 84.2%. Other reports β- Pachyman（ β- Pachyman) is the main component, accounting for 93% of the dry product. Triterpenoids include pachymic acid, humic acid, clofibric acid, odontogenic acid, abietic acid, and abietic acid. Fatty acids include caprylic acid and lauric acid. Other ingredients include ergosterol, gum, chitin, protein, fat, lecithin, etc.
1. Diuretic and detumescence effect
Lingsu is a new aldosterone receptor antagonist, which is beneficial to urine excretion, recovery of renal function and elimination of protein.
2. Effect on digestive system
The triterpenoids of Poria cocos enhanced the differentiation inducing activity of insulin, and the triterpenoids themselves also had differentiation inducing activity. Poria triterpenoids and their derivatives can inhibit vomit induced by oral copper sulfate in frogs.
3. Stone prevention
Poria cocos polysaccharide can effectively inhibit the formation and deposition of calcium oxalate crystals in the kidney of rats, and has a good anti stone effect.
4. Anti rejection effect
Poria cocos extract can obviously inhibit the acute rejection of heterotopic heart transplantation in rats.
5. Antibacterial and antiviral effects
100% filter paper of Poria cocos extract can inhibit Staphylococcus aureus, Staphylococcus albus, Pseudomonas aeruginosa, Bacillus anthracis, Escherichia coli, Streptococcus A and Streptococcus B.
6. Anticonvulsant effect
The total triterpenoids of Poria cocos can resist the maximum electric shock and pentylenetetrazole convulsions to varying degrees, which proves that the total triterpenoids of Poria cocos have obvious anticonvulsant effects.
7. Anti inflammatory effect
The total triterpenoids of Poria cocos can inhibit the acute inflammation such as auricle swelling in mice caused by xylene and the permeability of abdominal capillaries in mice, and also have a strong inhibitory effect on the subacute inflammation of cotton ball granuloma in rats. It shows that the total triterpenoids of Poria cocos is one of the main effective components of the anti-inflammatory effect of Poria cocos, and its mechanism may be related to the inhibition of phospholipase A2 activity by the triterpenoids contained in Poria cocos.
8. Whitening effect
White Poria cocos has significant inhibition on tyrosinase and is a competitive inhibition. Reducing melanin production by inhibiting tyrosinase activity may be one of the mechanisms of whitening traditional Chinese medicine.
