Views: 0 Author: Site Editor Publish Time: 2023-04-12 Origin: Site
Danshen extract is a dried root and rhizome extract of the labiate plant Danshen, which contains bioactive substances such as tanshinone, cryptotanshinone, isotanshinone, tanshinone, and tanshinol. It also contains vitamin A, E, and metal elements such as iron and potassium.
Salvia miltiorrhiza is a perennial erect herb of Lamiaceae and Salvia genus, with thick roots, vermilion outside, white inside, fleshy, leaves are often odd pinnate compound leaves, terminal or axillary racemes; The bracts are lanceolate, the calyx is bell-shaped, tinged with purple, the corolla is purple-blue, the style is far outstretched, the nutlets are black, oval, blooms from April to August, and sees fruit after flowering.
Salvia miltiorrhiza is distributed in Anhui, Shanxi, Hebei, Sichuan, Jiangsu and other places in China. In addition, Hubei, Gansu, Liaoning, Shaanxi, Shandong, Zhejiang, Henan, Jiangxi and other places. Japan is also distributed.
This type of root medicine contains tanshinone, which is a strong and meridian promoting agent. It has the equivalent effects of removing blood stasis, generating new energy, promoting blood circulation, and regulating menstruation. It is a gynecological medicine that mainly treats uterine bleeding, irregular menstruation, blood stasis, abdominal pain, menstrual pain, amenorrhea, and temple pain. It has a good effect on treating coronary heart disease. In addition, it can also treat neurological weakness, insomnia, joint pain, anemia, mastitis, lymphadenitis, arthritis, sores and boils, erysipelas, acute and chronic hepatitis, kidney kidney kidney disease, falls and injuries, advanced schistosomiasis, liver and spleen enlargement, and epilepsy. External use can also wash lacquer sores.
Tanshinone IIA, salvianolic acid B, cryptotanshinone: mainly fat-soluble non-quinone pigment compounds, such as tanshinone IIA, tanshinone IIB, cryptotanshinone and its isomers. Water-soluble phenolic acids such as protocatechualdehyde and danshensu. Among them, cryptotanshinone is an effective antibacterial ingredient.
1. Reduce endothelial damage
Salvia miltiorrhiza extract can reduce endothelial damage and promote endothelial repair in the process of acute cerebral infarction, pulmonary embolism, atherosclerosis and diabetes retinopathy.
2. Anti inflammatory effects
Danshen extract has good anti-inflammatory effects, and recent clinical observations and animal experiments have shown that it has certain anti-inflammatory effects in the process of viral myocarditis, bronchial asthma, cavitary pulmonary tuberculosis, arthritis, and acute coronary syndrome.
3. Improve microcirculation
Danshen extract can significantly improve microcirculation and be used for basic treatments such as cerebral ischemia, cerebral infarction, and ischemic bowel disease.
4. Regulate glucose and lipid metabolism
Salvia miltiorrhiza extract has a good regulatory effect on glucose and lipid metabolism. Domestic scholars often use Salvia miltiorrhiza extract to conduct clinical research on patients with diabetes and abnormal glucose tolerance.
5. Anti platelet aggregation
Studies have confirmed that Danshen and its extracts have certain anti-platelet aggregation effects in atherosclerosis, coronary heart disease angina pectoris, and pulmonary heart pain.
It has pharmacological effects such as dilating coronary arteries, increasing coronary flow, anti-myocardial ischemia, anti-myocardial infarction, anti-atherosclerosis, liver protection, anti-tumor, sedation, antibacterial and immune function suppression.
Take Salvia miltiorrhiza, grind it into coarse powder, heat it with ethanol and reflux it three times, filter it, merge the filtrate, recover ethanol under reduced pressure, and concentrate it into a thick paste with a relative density of 1.30~1.35 (60 ° C). Wash it with hot water until the washing solution is colorless, dry it at 80 ° C, and grind it into fine powder.