Rhubarb extract benefits and side effects
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Rhubarb extract benefits and side effects

Views: 0     Author: Site Editor     Publish Time: 2022-09-21      Origin: Site

The rhubarb extract is the dried root and rhizome extracts of the Polygonaceae plant rhubarb, tangute rhubarb or medicinal rhubarb. There are several varieties of rhubarb such as Chinese rhubarb, rhubarb, garden rhubarb, Himalayan rhubarb, Indian rhubarb, medicinal rhubarb and palm-leaf rhubarb.

Rhubarb is a common plant. Its rhizome is used for pharmaceutical and other functions, mainly for digestive system diseases, including constipation, diarrhea, heartburn, stomach pain, gastrointestinal bleeding, etc. Some people use rhubarb extract to make their bowel movements less stressful and smoother; it also reduces pain from anal fissures and hemorrhoids. Rhubarb is also sometimes used on the skin, such as lip sores. In food, rhubarb stems can be eaten in pies and other foods.

The role of dehydrated rhubarb powder

1. Effects on the digestive system

(1) Diarrhea effect: The main action site of diarrhea is in the large intestine. The active ingredient of rhubarb purgative is anthracene glycosides, mainly sennoside. Sennoside is decomposed under the action of intestinal bacterial enzymes to produce rhein anthrone, which can stimulate the mucosa of the large intestine and increase the peristalsis and diarrhea. In addition, it can also inhibit Na+, K+-ATP enzymes on the intestinal cell membrane, hinder Na+ transport, increase the osmotic pressure in the intestine, retain a lot of water, and promote intestinal peristalsis and diarrhea.

(2) Gallbladder and hepatoprotective effects: Rhubarb extract can promote bile secretion, and can increase the content of bilirubin and bile acid in bile, relieve bile duct sphincter spasm, enhance duodenum and bile duct relaxation, dredge bile duct and microscopic Bile that accumulates in the bile ducts.best rhubarb extract -HerbKey

2. Effects on the blood system

(1) Hemostatic effect: Rhubarb extract has exact hemostatic effect and quick effect. The active ingredients are α-catechin and gallic acid. The mechanism of action is to promote platelet adhesion and aggregation; increase platelet count and fibrinogen content; reduce antithrombin Ⅲ activity; constrict local blood vessels.

(2) hypolipidemic effect: rhubarb extract can reduce the levels of total cholesterol, triacylglycerol, low density lipoprotein, very low density lipoprotein and lipid peroxide. The rhubarb was made into granules and served continuously for 2 months. The lipid-lowering effect was good, and no adverse reactions were seen.

(3) Blood-activating effect: Rhubarb extract has a blood-thinning effect, which may be through the effect of plasma osmotic pressure to promote the transfer of extracellular fluid into the blood vessels, thereby diluting the blood, resulting in the reduction of blood cells, and the decrease in blood viscosity, thereby enhancing the micro-organism. circulation, to achieve the purpose of blood circulation.

3. Anti-infective effect Rhubarb extract has inhibitory effect on a variety of gram-positive and negative bacteria in vitro, especially sensitive to paratyphoid bacillus, dysentery bacillus, etc. It also has a certain killing effect on hepatitis B virus, a variety of fungi, amoeba, and Trichomonas vaginalis. The main antibacterial ingredients are rhein, emodin and aloe-emodin. The antibacterial mechanism is mainly to inhibit the oxidation and dehydrogenation of the intermediate products of bacterial sugar metabolism, inhibit the synthesis of proteins and nucleic acids, inhibit the bacterial biological oxidase system, and induce interferon.

4. Antipyretic effect In the acute phase of acute or infectious diseases, the application of rhubarb extract treatment can play a cooling effect, and the cooling is stable, without adverse reactions such as profuse sweating or collapse. Its antipyretic mechanism is: inhibiting the synthesis of prostaglandin E in the body temperature center, reducing the content of cyclic glycoside nucleic acid, expanding peripheral blood vessels and increasing heat dissipation to achieve the purpose of cooling.

5. Immunoregulatory effect The influence of rhubarb extract on immune function has a two-way regulatory effect, with different degrees of immunosuppression, and has inhibitory or blocking effects on cellular immunity and humoral immunity. Long-term application can cause thymus, spleen, Atrophy of immune organs such as lymph nodes. In addition, rhubarb can increase the phagocytosis of macrophages in the peritoneal cavity of mice, promote the production of interferon in the human body, and improve the immunity, so as to achieve the purpose of clearing the virus.

6. Other functions More and more scholars at home and abroad have proved that the tannin contained in rhubarb has a good antioxidant effect. Rhubarb polysaccharide also has obvious inhibitory effect on tumor, and also has hypolipidemic, diuretic, anti-inflammatory and antihypertensive effects.

Rhubarb extract powder side effects

Rhubarb is eaten as food in some places. Most people who use rhubarb for a long time may experience some side effects such as stomach pain, diarrhea and uterine contractions. It can even lead to muscle weakness, bone loss, potassium loss and irregular heartbeat.

People who take products containing rhubarb have had cases of kidney failure. But it's not quite sure whether rhubarb is the real cause of kidney failure.

Special Notes and Warnings:

Children: Rhubarb may not be safe for children. One report said a 4-year-old died after eating rhubarb leaves. Rhubarb leaves contain high amounts of oxalic acid, which can be fatal if taken in high enough doses. Because of their small size, children are at the highest risk of developing oxalic acidosis after eating rhubarb leaves.

Pregnant and breastfeeding women: Pregnant and breastfeeding women are advised to consume less rhubarb as it may not be safe to consume at this stage.

People with diarrhea or constipation: People with diarrhea and constipation should not use rhubarb extract because rhubarb itself has a laxative, laxative effect that can make diarrhea or constipation worse.

Gastrointestinal disorders: Do not take rhubarb extract if you have intestinal obstruction, appendicitis; unexplained stomach pain or intestinal inflammation, including Crohn's disease, colitis, and irritable bowel syndrome.

People with kidney failure: Rhubarb contains a chemical that may be harmful to the kidneys. In India, there has been a case of a person suffering from kidney failure who died after taking rhubarb. If you already have kidney disease, don't take the risk of taking rhubarb.

Kidney stones: Rhubarb contains a chemical that can be converted into kidney stones. Do not take rhubarb if you have ever had kidney stones.

Liver problems: Rhubarb can worsen liver function in people who already have liver disease. People with liver problems should avoid rhubarb.