Silicified Microcrystalline Cellulose Medicinal Excipients
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Silicified Microcrystalline Cellulose Medicinal Excipients

Product Name:Silicified microcrystalline cellulose
Appearance:white powder

What is it?

Microcrystalline cellulose (C6H10O5)n is refined wood pulp. It is a white, free-flowing powder. Chemically, it is an inert substance, it is not degraded during digestion and has no appreciable absorption. In large quantities it provides dietary bulk and may lead to a laxative effect.

Microcrystalline cellulose is a commonly used excipient in the pharmaceutical industry. It has excellent compressibility properties and it is used in solid dose forms, such as tablets. Tablets can be formed that are hard, but dissolve quickly. Microcrystalline cellulose is the same as cellulose, except that it meets USP standards. Silicified microcrystalline cellulose (SMCC) is a novel tableting excipient which can improve binding capability as a material and in tablet formulations. The material also shows improved resistance to the degrading effects of magnesium stearate compared with regular microcrystalline cellulose.

It is also found in many processed food products, and may be used as an anti-caking agent, stabilizer, texture modifier, or suspending agent among other uses. According to the Select Committee on GRAS Substances, microcrystalline cellulose is generally regarded as safe when used in normal quantities.