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It is extracted by hydro-distillation from the roots and rhizomes of Valeriana officinalis, a plant of the septoriaceae family. It has a special fragrance of wood, oil paste and musk.
Green to brown liquid with special aroma like wood, cream and musk. The relative density (d15) is 0.953~0.990, the refractive index (nD20) is 1.4861~1.5021, the acid value is about 5.0, and the ester value is about 130. 1ml sample is soluble in 0.5~1.5ml, 90% ethanol. It also has the functions of expelling wind, exciting and antispasmodic.
1. Valerian has a sedative effect, can strengthen the inhibitory process of the cerebral cortex, reduce reflex excitability and relieve smooth muscle spasm. It can be used in combination with bromine to treat various neuroexcitability, cardiovascular neurosis, hyperthyroidism, etc. It has a sedative effect on frogs, mice and rabbits. It also shows some stabilizing effect on free-ranging cats, reducing their excitement and aggression, while their reaction to the outside world is unaffected. Valerian itself does not cause sleep in animals, but it enhances the sleeping effect of barbiturates and inhibits the general activity of animals.
2. Effects on circulation and respiration Certain components of valerian have the effect of lowering blood pressure in animals (dogs, cats, rabbits and mice), which is related to its parasympathetic-like effect, blocking the carotid sinus reflex and inhibiting the central nervous system. In isolated frog hearts, it inhibits the contractile effect of cardiac glycosides on frog hearts, but does not counteract the arrhythmias induced by aconitine. Appropriate doses were administered intravenously or rectally to stimulate respiration in cats or rabbits, but had no stimulatory effect during deep anesthesia with chloral hydrate. Large doses also inhibit respiration in normal animals.
3. It has some antidiuretic effects. Intravenous injection of the extract in dogs accelerates the blood clotting process in vivo, but has no effect in vitro. The extract has an inhibitory effect on the isolated small intestine and an excitatory effect at high doses, which can be blocked by atropine.
It is extracted by hydro-distillation from the roots and rhizomes of Valeriana officinalis, a plant of the septoriaceae family. It has a special fragrance of wood, oil paste and musk.
Green to brown liquid with special aroma like wood, cream and musk. The relative density (d15) is 0.953~0.990, the refractive index (nD20) is 1.4861~1.5021, the acid value is about 5.0, and the ester value is about 130. 1ml sample is soluble in 0.5~1.5ml, 90% ethanol. It also has the functions of expelling wind, exciting and antispasmodic.
1. Valerian has a sedative effect, can strengthen the inhibitory process of the cerebral cortex, reduce reflex excitability and relieve smooth muscle spasm. It can be used in combination with bromine to treat various neuroexcitability, cardiovascular neurosis, hyperthyroidism, etc. It has a sedative effect on frogs, mice and rabbits. It also shows some stabilizing effect on free-ranging cats, reducing their excitement and aggression, while their reaction to the outside world is unaffected. Valerian itself does not cause sleep in animals, but it enhances the sleeping effect of barbiturates and inhibits the general activity of animals.
2. Effects on circulation and respiration Certain components of valerian have the effect of lowering blood pressure in animals (dogs, cats, rabbits and mice), which is related to its parasympathetic-like effect, blocking the carotid sinus reflex and inhibiting the central nervous system. In isolated frog hearts, it inhibits the contractile effect of cardiac glycosides on frog hearts, but does not counteract the arrhythmias induced by aconitine. Appropriate doses were administered intravenously or rectally to stimulate respiration in cats or rabbits, but had no stimulatory effect during deep anesthesia with chloral hydrate. Large doses also inhibit respiration in normal animals.
3. It has some antidiuretic effects. Intravenous injection of the extract in dogs accelerates the blood clotting process in vivo, but has no effect in vitro. The extract has an inhibitory effect on the isolated small intestine and an excitatory effect at high doses, which can be blocked by atropine.
