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Vitamin B1, also known as thiamine, it is one of the B vitamins. It can promote normal glucose metabolism and it is necessary for maintaining normal functions of nerve conduction, heart and gastrointestinal tract. It combines with adenosine triphosphate to form vitamin B1 pyrophosphate (thiamine diphosphate, or coenzyme), which is necessary for carbohydrate metabolism. The lack of this coenzyme can lead to the inhibition of oxidative metabolism and the formation of pyruvate and lactic acid accumulation, affecting the energy supply of the body. Vitamin B1 can also inhibit the activity of cholinesterase; The increase of cholinesterase activity and the acceleration of acetylcholine hydrolysis lead to the disturbance of nerve impulse conduction and affect the gastrointestinal and myocardial functions. Vitamin B1 is rich in seed coat and embryo, such as rice bran, wheat bran, etc; The content of coarse grains is higher than that of refined rice or white flour. Others such as yeast, lean meat, peanuts, soybeans, liver, whole wheat, fresh vegetables such as cabbage, celery, plantain seed, coix seed all contain rich vitamin B1.
There are several sources of VB1. First, the content of VB1 in grains, beans, hard fruit and dry yeast is relatively rich, so the content of VB1 in brown rice and flour with bran is higher than that in refined white rice; Second, VB1 is contained in the viscera of animals such as liver, kidney, lean meat and egg yolk; Third, some vegetables, such as celery and laver, have different levels of VB1.
1. beriberi
In the absence of VB1, glucose metabolism is impaired, glucose oxidation is blocked, and the accumulation of acetolactate is formed, which affects the energy supply of the body, and clinical symptoms of digestive and circulatory systems occur. Beriberi was discovered around 1630. In 1882, a Japanese general observed that many sailors had anorexia, constipation, slow bowel movement, abdominal distension and other symptoms, and noticed that it was related to food. Later, after he added rice, meat and vegetables to the drink, he found that there were many fewer people with these symptoms. It has been confirmed that these symptoms are caused by lack of VB1. Lack of VB1 often presents digestive system symptoms such as poor appetite, constipation, slow intestinal peristalsis, and abdominal distension; The cardiovascular system is characterized by tachycardia, edema, cardiac hypertrophy and dilation; The nervous system is characterized by fatigue, memory loss, insomnia, and the severe cases may have central and peripheral inflammatory symptoms or mental disorders. Some patients may also have symmetrical abnormal toe sensation: foot burning pain, gastrocnemius spasm, foot pain and other symptoms. In the treatment of beriberi, the cause of disease should be corrected first, which can be treated symptomatically by supplementing vitamin B1, diuresis and detumescence, and regulating gastrointestinal tract.
2. Lactic acid accumulation
VB1 plays an important role in glucose metabolism and maintaining the normal function of the nervous system in the process of human metabolism. Lack of VB1 during lactation will lead to metabolic disorders of carbohydrates, accumulation of other metabolites of lactic acid, and accumulation of harmful substances in breast milk, which is easy to cause toxic reactions in infants.
It is suitable for vitamin B1 deficiency and it has the function of maintaining normal glucose metabolism and nerve conduction. It is also used as an auxiliary treatment for indigestion and neuritis.
Vitamin B1, also known as thiamine, it is one of the B vitamins. It can promote normal glucose metabolism and it is necessary for maintaining normal functions of nerve conduction, heart and gastrointestinal tract. It combines with adenosine triphosphate to form vitamin B1 pyrophosphate (thiamine diphosphate, or coenzyme), which is necessary for carbohydrate metabolism. The lack of this coenzyme can lead to the inhibition of oxidative metabolism and the formation of pyruvate and lactic acid accumulation, affecting the energy supply of the body. Vitamin B1 can also inhibit the activity of cholinesterase; The increase of cholinesterase activity and the acceleration of acetylcholine hydrolysis lead to the disturbance of nerve impulse conduction and affect the gastrointestinal and myocardial functions. Vitamin B1 is rich in seed coat and embryo, such as rice bran, wheat bran, etc; The content of coarse grains is higher than that of refined rice or white flour. Others such as yeast, lean meat, peanuts, soybeans, liver, whole wheat, fresh vegetables such as cabbage, celery, plantain seed, coix seed all contain rich vitamin B1.
There are several sources of VB1. First, the content of VB1 in grains, beans, hard fruit and dry yeast is relatively rich, so the content of VB1 in brown rice and flour with bran is higher than that in refined white rice; Second, VB1 is contained in the viscera of animals such as liver, kidney, lean meat and egg yolk; Third, some vegetables, such as celery and laver, have different levels of VB1.
1. beriberi
In the absence of VB1, glucose metabolism is impaired, glucose oxidation is blocked, and the accumulation of acetolactate is formed, which affects the energy supply of the body, and clinical symptoms of digestive and circulatory systems occur. Beriberi was discovered around 1630. In 1882, a Japanese general observed that many sailors had anorexia, constipation, slow bowel movement, abdominal distension and other symptoms, and noticed that it was related to food. Later, after he added rice, meat and vegetables to the drink, he found that there were many fewer people with these symptoms. It has been confirmed that these symptoms are caused by lack of VB1. Lack of VB1 often presents digestive system symptoms such as poor appetite, constipation, slow intestinal peristalsis, and abdominal distension; The cardiovascular system is characterized by tachycardia, edema, cardiac hypertrophy and dilation; The nervous system is characterized by fatigue, memory loss, insomnia, and the severe cases may have central and peripheral inflammatory symptoms or mental disorders. Some patients may also have symmetrical abnormal toe sensation: foot burning pain, gastrocnemius spasm, foot pain and other symptoms. In the treatment of beriberi, the cause of disease should be corrected first, which can be treated symptomatically by supplementing vitamin B1, diuresis and detumescence, and regulating gastrointestinal tract.
2. Lactic acid accumulation
VB1 plays an important role in glucose metabolism and maintaining the normal function of the nervous system in the process of human metabolism. Lack of VB1 during lactation will lead to metabolic disorders of carbohydrates, accumulation of other metabolites of lactic acid, and accumulation of harmful substances in breast milk, which is easy to cause toxic reactions in infants.
It is suitable for vitamin B1 deficiency and it has the function of maintaining normal glucose metabolism and nerve conduction. It is also used as an auxiliary treatment for indigestion and neuritis.
