Views: 0 Author: Site Editor Publish Time: 2022-11-02 Origin: Site
Vitamin B6, also known as pyridoxine, includes pyridoxine, pyridoxal and pyridoxamine, which exist in the body in the form of phosphate. It is a water-soluble Vitamin, which is easy to damage when exposed to light or alkali, and is not resistant to high temperature. It was named Vitamin B6 in 1936. Vitamin B6 is a colorless crystal, easily soluble in water and ethanol, stable in acid solution, easy to destroy in alkali solution, heat resistant to pyridoxine, and heat resistant to pyridoxal and pyridoxamine. Vitamin B6 is abundant in yeast, liver, grains, meat, fish, eggs, beans and peanuts. Vitamin B6 is a component of some coenzymes in the human body and participates in a variety of metabolic reactions, especially closely related to amino acid metabolism. Vitamin B6 was used clinically to prevent and treat pregnancy vomiting and radiation sickness vomiting.
In the 19th century, pellagra was found to be caused by nicotinic acid deficiency. In 1926, another vitamin was found to be deficient in the feed, which also caused pellagra in mice. The Hungarian scientist Gyorgy discovered vitamin B6 in 1934, but its chemical structure was not determined and artificially synthesized until 1939.
Vitamin B6 comes from a wide range of food sources, including animal and plant foods. Generally, meat, whole grain products (especially wheat), vegetables and nuts are high in content. The bioavailability of vitamin B6 in food from animal sources is better than that of food from plant sources. In animal and plant foods, the content is small, yeast powder is the most, rice bran or white rice is also much, followed by meat, poultry, fish, potatoes, sweet potatoes and vegetables.
The amount of vitamin B6 in every 100g edible part of various foods is as follows: yeast powder 3.67mg, skimmed rice bran 2.91mg, white rice 2.79mg, flax meal 1.25mg, cheese 0.8 ～ 0.04mg, carrot 0.7mg, fish 0.45mg, whole wheat extract 0.4 ～ 0.7mg, meat 0.3 ～ 0.08mg, milk 0.3 ～ 0.03mg, egg 0.25mg, spinach 0.22mg, sweet potato 0.14 ～ 0.23mg, pea 0.16mg, soybean 0.1mg, orange 0.05mg.
Generally speaking, the microorganisms (bacteria) in human and animal intestines can synthesize vitamin B6, but the amount of vitamin B6 is very small, so it should be supplemented from food. In fact, its demand is closely related to the amount of protein intake. If you eat a lot of meat and fish, you should remember to supplement a large amount of vitamin B6 to avoid vitamin B6 deficiency and the occurrence of chronic diseases.
Vitamin b6 is an essential substance for human fat and sugar metabolism, and female estrogen metabolism also needs vitamin b6, so it is of great benefit to the prevention and treatment of certain gynecological diseases. Many women will be pessimistic, irritable, and feel weak due to taking the contraceptive pill. A daily supplement of 60 mg can alleviate the symptoms. Some women also suffer from premenstrual tension syndrome, which is characterized by swollen eyelids, hands and feet before menstruation, insomnia and amnesia. The symptoms can be completely relieved after taking 50~100 mg vitamin b6 every day. Foods rich in b6 include tuna, lean steak, chicken breast, bananas, peanuts, beef, etc.
It mainly participates in nearly 100 kinds of enzyme reactions in the form of phosphopyridine polyaldehyde (PLP). Most of them are related to amino acid metabolism, including transamination, decarboxylation, side chain cleavage, dehydration and trans sulfurization. These biochemical functions involve many aspects.
1. It is involved in protein synthesis and catabolism, as well as all amino acid metabolism, such as the metabolism of heme and the synthesis of nicotinic acid from tryptophan.
2. It participates in gluconeogenesis and UFA metabolism. It is related to the metabolism of glycogen, sphingomyelin and steroids.
3. Participates in certain neurotransmitters (serotonin, taurine, dopamine, norepinephrine and γ- Aminobutyric acid).
4. Metabolism of vitamin B6 and one carbon unit, vitamin B12 and folate can cause megaloblastic anemia if they have metabolic disorders.
5. It participates in the synthesis of nucleic acid and DNA. Lack of DNA will damage the synthesis of DNA. This process is very important for maintaining appropriate immune function.
6. Vitamin B6 is closely related to vitamin B2, and vitamin B6 deficiency is often accompanied by vitamin B2 symptoms.
7. It is involved in the conversion of homocysteine to methionine and has the effect of reducing chronic diseases. Mild hyperhomocysteinemia is considered as a possible risk factor for vascular diseases. The intervention of vitamin B6 can reduce the plasma homocysteine content.