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Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin, which exists in some fruits, vegetables and meat and can be used as a dietary supplement. Unlike most animals, humans are unable to synthesize internally and therefore require external ingestion.
1. Vitamin C has the effect of adjusting skin texture and reducing color spots.
2. Vitamin C helps prevent severe cold complications.
3. Vitamin C affects cells inside and outside the body, and its antioxidant properties are beneficial during aging.
1. Character: Vitamin C is white crystal or crystalline powder, odorless, sour in taste, and gradually yellowish after a long time. It is easily soluble in water, acidic, slightly soluble in ethanol, and insoluble in chloroform or ether.
2. Acidity: The molecular structure of vitamin C has an alkene glycol structure. Due to the conjugation effect, the acidity of C2-OH is extremely weak (pK2=11.57), while that of C3-OH is strong (pK1=4.17). Therefore, the vitamin generally behaves as a monobasic acid, which can react with sodium bicarbonate as sodium salt.
3. Optical activity: The molecular structure of vitamin C contains two chiral carbon atoms, so it has optical activity. According to the method (ChP2015 general rule 0621), the specific rotation of the aqueous solution containing 0.10g/mL of this product is+20.50 °~+21.50 °.
4. Reducibility: The alkenyl glycol group in the molecular structure has extremely strong reducibility and it is easy to be oxidized to diketone group to become dehydroascorbic acid. Dehydroascorbic acid can be further hydrolyzed in alkaline or strong acidic solutions to form diketogulonic acid and lose its activity.
5. Hydrolyzability: The action of vitamin C and sodium carbonate can generate monosodium salt without hydrolysis. The double bond makes the lactone ring stable, but in strong alkaline solution, the lactone ring can be hydrolyzed to form keto acid salt.
6. Properties of sugars: The structure of vitamin C is similar to that of sugar, so it has a reaction of carbohydrate properties.
7. Ultraviolet absorption: There are conjugated double bonds in the vitamin C molecule, and its dilute hydrochloric acid solution has the maximum absorption at 243nm. If it is in neutral or alkaline conditions, the red shift is 265nm.
The synthesis of collagen requires the participation of vitamin C. If vitamin C is deficient, collagen cannot be synthesized normally, resulting in impaired cell connection and scurvy. Insufficient vitamin C in the body will easily rupture the capillaries, and blood will flow to the adjacent tissues. This situation occurs on the surface of the skin, resulting in congestion and purple sputum; if it occurs in the body, it will cause pain and joint pain. In severe cases, there may be bleeding under the stomach, intestines, nose, kidneys and periosteum, and even death. Lack of vitamin C will cause gum recession and bleeding; induce arteriosclerosis and anemia. Because if vitamin C reduces ferric iron that is difficult to absorb into ferrous iron, it can promote the absorption of iron in the intestine and improve the utilization rate of iron in the liver, which is helpful for the treatment of iron deficiency anemia. Lack of vitamin C will reduce the body's immunity and the body's emergency ability.
Excessive use of vitamin C supplements in a short period of time may cause side effects such as polyuria, diarrhea, and skin rash; long-term use of excessive vitamin C supplements may lead to oxalic acid and uric acid stones; excessive vitamin C supplementation in children is prone to bone diseases ; If a one-time intake of vitamin C2500~5000mg or even higher, it may cause a large number of red blood cells to rupture, resulting in critical phenomena such as hemolysis.
Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin, which exists in some fruits, vegetables and meat and can be used as a dietary supplement. Unlike most animals, humans are unable to synthesize internally and therefore require external ingestion.
1. Vitamin C has the effect of adjusting skin texture and reducing color spots.
2. Vitamin C helps prevent severe cold complications.
3. Vitamin C affects cells inside and outside the body, and its antioxidant properties are beneficial during aging.
1. Character: Vitamin C is white crystal or crystalline powder, odorless, sour in taste, and gradually yellowish after a long time. It is easily soluble in water, acidic, slightly soluble in ethanol, and insoluble in chloroform or ether.
2. Acidity: The molecular structure of vitamin C has an alkene glycol structure. Due to the conjugation effect, the acidity of C2-OH is extremely weak (pK2=11.57), while that of C3-OH is strong (pK1=4.17). Therefore, the vitamin generally behaves as a monobasic acid, which can react with sodium bicarbonate as sodium salt.
3. Optical activity: The molecular structure of vitamin C contains two chiral carbon atoms, so it has optical activity. According to the method (ChP2015 general rule 0621), the specific rotation of the aqueous solution containing 0.10g/mL of this product is+20.50 °~+21.50 °.
4. Reducibility: The alkenyl glycol group in the molecular structure has extremely strong reducibility and it is easy to be oxidized to diketone group to become dehydroascorbic acid. Dehydroascorbic acid can be further hydrolyzed in alkaline or strong acidic solutions to form diketogulonic acid and lose its activity.
5. Hydrolyzability: The action of vitamin C and sodium carbonate can generate monosodium salt without hydrolysis. The double bond makes the lactone ring stable, but in strong alkaline solution, the lactone ring can be hydrolyzed to form keto acid salt.
6. Properties of sugars: The structure of vitamin C is similar to that of sugar, so it has a reaction of carbohydrate properties.
7. Ultraviolet absorption: There are conjugated double bonds in the vitamin C molecule, and its dilute hydrochloric acid solution has the maximum absorption at 243nm. If it is in neutral or alkaline conditions, the red shift is 265nm.
The synthesis of collagen requires the participation of vitamin C. If vitamin C is deficient, collagen cannot be synthesized normally, resulting in impaired cell connection and scurvy. Insufficient vitamin C in the body will easily rupture the capillaries, and blood will flow to the adjacent tissues. This situation occurs on the surface of the skin, resulting in congestion and purple sputum; if it occurs in the body, it will cause pain and joint pain. In severe cases, there may be bleeding under the stomach, intestines, nose, kidneys and periosteum, and even death. Lack of vitamin C will cause gum recession and bleeding; induce arteriosclerosis and anemia. Because if vitamin C reduces ferric iron that is difficult to absorb into ferrous iron, it can promote the absorption of iron in the intestine and improve the utilization rate of iron in the liver, which is helpful for the treatment of iron deficiency anemia. Lack of vitamin C will reduce the body's immunity and the body's emergency ability.
Excessive use of vitamin C supplements in a short period of time may cause side effects such as polyuria, diarrhea, and skin rash; long-term use of excessive vitamin C supplements may lead to oxalic acid and uric acid stones; excessive vitamin C supplementation in children is prone to bone diseases ; If a one-time intake of vitamin C2500~5000mg or even higher, it may cause a large number of red blood cells to rupture, resulting in critical phenomena such as hemolysis.
