Views: 0 Author: Site Editor Publish Time: 2022-11-18 Origin: Site
Gynostemma pentaphyllum extract is more than 50 kinds of gypenosides isolated from Gynostemma pentaphyllum. Like ginsenosides, it belongs to tetracyclic triterpenoid saponins. Traditional Chinese medicine believes that Gynostemma pentaphyllum tastes bitter and cold, and has the functions of clearing heat and detoxifying, tonifying qi, relieving cough, and eliminating phlegm.
More than 50 species of gypenosides have been isolated from Gynostemma pentaphyllum. Like ginsenosides, they belong to the tetracyclic triterpenoid masaponins, among which gypenosides III, IV, VII, and XII are the same substance as ginsenosides Rb1, Rb3, Rd, and F2, respectively. , gypenoside V-AH is the same as ginsenoside Rg3, and gypenoside I is decomposed by enzyme to obtain ginsenoside K. Ginsenoside K is obtained by pharmacological and clinical decomposition.
Pharmacological and clinical studies show that Gynostemma pentaphyllum is almost non-toxic and has no side effects. It has the following functions: (1) anti-cancer, inhibiting the proliferation of cancer cells such as liver cancer, lung cancer, uterine cancer and melanoma; (2) Anti aging effect can enhance the immune function of the body; (3) Hypolipidemic effect; (4) Prevention and treatment of side effects of glucocorticoid, etc.
Soak in 10 times the amount of 75% ethanol for 12 hours, and ultrasonically extract 3 times, 80 minutes each time.
Traditional Chinese medicine believes that Gynostemma pentaphyllum tastes bitter and cold, and has the functions of clearing heat and detoxifying, tonifying qi, relieving cough, and eliminating phlegm. Modern pharmacological studies have proved that Gynostemma pentaphyllum has the functions of lowering blood fat, lowering blood pressure, increasing coronary artery and cerebral blood flow, anti-aging, strengthening, enhancing immunity, protecting liver, calming and pain relieving, anti ulcer, etc. It has a significant effect on the prevention and treatment of atherosclerosis, hypertension, coronary heart disease, stroke, diabetes, obesity, chronic hepatitis, chronic atrophic gastritis, chronic cholecystitis, ulcer disease, bronchitis and other diseases.
In 1976, Japanese scientists extracted the total saponins from Gynostemma pentaphyllum. Gypenoside GP is a mixture of saponins extracted from Gypenoside plants. Its chemical composition is complex, and its basic chemical structure is similar to the dammarane structure of the skeleton tetracyclic triterpene of ginsenoside, some of which are identical with ginsenoside. Through extensive pharmacological studies, it has been found that it has a strong anti atherosclerosis and hypolipidemic effect, and most of the new drugs developed have this effect.
Animal experiments in vivo and in vitro found that GP has a significant hepatoprotective effect; further research found that GP can significantly improve the cellular immune function of patients with chronic hepatitis B and reduce the level of lipid peroxygen compounds in patients. Therefore, it is inferred that GP can improve the immune function of the body and reduce the production of lipid peroxides is the main mechanism for the effective treatment of chronic hepatitis B. Among them, there are many studies on the treatment of atherosclerosis. In addition, Gynostemma pentaphyllum also has the effect of anti-mutation of genetic material DNA, which can exert the ability of cells to repair damage, promote the return of cancer cells to normal, prevent tumor recurrence and metastasis, inhibit the proliferation of almost all cancer cells, and enhance the immune function of patients. Therefore, it has become a rookie in anti-cancer plants and is widely used in anti-cancer and anti-cancer.
In addition, Gynostemma pentaphyllum also has the functions of anti-inflammatory and detoxification, relieving cough and expectorant. Clinically, it is mainly used for chronic bronchitis, and it is also compatible with other traditional Chinese medicines for lowering blood fat, enhancing immunity, anti-cancer, anti-aging, etc. It has a wide range of applications. The Gynostemma pentaphylla prescription preparations researched and developed mainly have the following dosage forms: tablets, granules, mixtures, oral liquids, capsules, injections, etc.
Because of the habit of drinking Gynostemma pentaphyllum tea in China for a long time, many manufacturers are producing Gynostemma pentaphyllum health drinks. There are not many enterprises extracting Gynostemma pentaphyllum saponins. However, in recent years, some new drugs for lowering blood lipid and treating cardiovascular diseases have been developed.
Gynostemma pentaphyllum has important medicinal value, and our country is rich in medicinal resources. It will have broad prospects to make full use of Gynostemma pentaphyllum drugs and series of health products.
